PKB, or protein kinase B, is a serine/threonine kinase vital for cell regulation. Specifically, it is also known as AKT.
Understanding PKB/AKT
PKB plays a crucial role in various cellular processes. It acts by adding phosphate groups (phosphorylation) to target proteins. This modification can change the protein's activity, which in turn affects the cell.
Key Functions of PKB/AKT
According to the provided reference, PKB, also known as AKT, is involved in:
- Cell Metabolism: Regulating the breakdown and synthesis of molecules in the cell.
- Cell Cycle Progression: Controlling the sequence of events leading to cell division.
- Growth and Survival: Promoting cell growth and preventing programmed cell death (apoptosis).
How PKB Works
PKB's actions are carried out by phosphorylating numerous proteins located within the cytoplasm and the nucleus of the cell. Through this phosphorylation, PKB influences a wide range of functions.
Importance of PKB
PKB's role in cell growth, survival, and metabolism is vital for maintaining cell health and organismal well-being. Its dysregulation is linked to diseases such as cancer, highlighting its importance in biological studies.
Summary Table of PKB
| Aspect | Details |
|---|---|
| Full Name | Protein Kinase B |
| Alternative Name | AKT |
| Type | Serine/threonine kinase |
| Function | Phosphorylates proteins to regulate metabolism, cell cycle, growth, and survival. |
| Location | Cytosol and nucleus |
