The function of RAC, specifically Rac GTPases, is to transduce signals and control essential cellular functions. These small G-proteins play a crucial role in various cell processes.
RAC's Role in Cellular Processes
Rac GTPases are involved in transducing signals from several receptors. According to the reference, these include:
- Tyrosine-kinase receptors
- G-protein-coupled receptors (GPCRs)
- Integrins
Furthermore, Rac proteins significantly influence several essential cellular functions, including:
- Motility: Enabling cells to move and migrate.
- Adhesion: Regulating how cells attach to each other and their surroundings.
- Proliferation: Controlling cell growth and division.
Summary Table of RAC Functions
| Function | Description |
|---|---|
| Signal Transduction | Relays signals from tyrosine-kinase, GPCRs, and integrins. |
| Motility | Controls cell movement and migration. |
| Adhesion | Regulates cell attachment to other cells and the extracellular matrix. |
| Proliferation | Influences cell growth and division. |
Because of these important functions, Rac GTPases are widely implicated in tumorigenesis and metastasis.
