askvity

Does CSF have hemoglobin?

Published in Cerebrospinal Fluid Composition 1 min read

Yes, CSF can have hemoglobin, especially in certain conditions.

The provided reference discusses cell-free hemoglobin in the cerebrospinal fluid (CSF-Hb). This suggests that hemoglobin can indeed be present in the CSF.

CSF-Hb and Brain Injury

According to the reference, CSF-Hb may be a key factor contributing to secondary brain injury after aneurysmal subarachnoid hemorrhage (aSAH). This implies that the presence of hemoglobin in the CSF is not normal but rather a consequence of a medical condition, such as bleeding in the brain. The body has mechanisms to deal with CSF-Hb, such as haptoglobin scavenging, which can help mitigate cerebrovascular disruption.

In Summary

  • Hemoglobin is not normally present in CSF.
  • However, in conditions like aSAH, cell-free hemoglobin (CSF-Hb) can be found in the CSF.
  • CSF-Hb can contribute to further brain injury.
  • The body has natural mechanisms to remove CSF-Hb.

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