cGMP (cyclic guanosine monophosphate) is produced in various locations within the body. Based on the provided reference, cGMP is produced in the olfactory system.
Specifically, in the olfactory system, cGMP synthesis occurs via two types of guanylyl cyclase:
- Membrane guanylyl cyclase (mGC)
- Soluble guanylyl cyclase (sGC)
Studies indicate that nitric oxide (NO), acting as a neurotransmitter, activates sGC, which then leads to cGMP synthesis in the olfactory system.