The provided reference relates to the administration of adenosine, not how to draw its chemical structure. Therefore, the question is being interpreted as: How do you draw the chemical structure of adenosine? This involves depicting its molecular components and their arrangement.
Adenosine is a nucleoside composed of adenine attached to a ribose sugar. Here's a breakdown of drawing its structure:
Drawing Adenosine: A Step-by-Step Guide
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Adenine Base: Begin by drawing the adenine base. Adenine is a purine derivative, consisting of two fused rings.
- Draw a six-membered ring (pyrimidine).
- Next, fuse a five-membered ring (imidazole) to the pyrimidine ring.
- Add nitrogen atoms at positions 1, 3, 7, and 9 within the fused ring system.
- Place an amino group (-NH2) at position 6 of the pyrimidine ring.
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Ribose Sugar: Draw the ribose sugar in its furanose (five-membered ring) form.
- Start with a five-membered ring containing an oxygen atom.
- Add hydroxyl groups (-OH) to the 2', 3', and 5' positions.
- Add a hydrogen atom to the 1', 2', 3', and 4' positions where needed to satisfy carbon's valence.
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Glycosidic Bond: Connect the adenine base to the ribose sugar.
- The nitrogen atom at position 9 of the adenine base will be bonded to the carbon atom at position 1' of the ribose sugar. This creates a β-N9-glycosidic bond. Remove a water molecule (H2O) to show that the bond has formed (condensation reaction).
Example: Adenosine Administration
While this addresses drawing the chemical structure, the reference discusses drawing up adenosine for intravenous administration. To do this, per the reference:
- Combine adenosine and saline: "Draw up the adenosine AND the normal saline in the same 20-mL syringe".
- Administer via fast IV push. The combined solution is administered quickly through an IV line.
