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Is potassium a cofactor?

Published in Cofactor Chemistry 1 min read

Yes, potassium is a cofactor.

Potassium as a Cofactor

Potassium ions (K+) act as activators and play a specific role as cofactors. Here's a breakdown:

  • Specific Enzyme: Potassium functions as a cofactor for the enzyme pyruvate kinase.
  • Metabolic Pathway: This enzyme is critical in the glycolysis pathway, a central process in energy production.
  • Nature of Interaction: Importantly, potassium does not form permanent bonds with the enzyme. It is involved in the activation process, facilitating the enzyme's function without becoming permanently attached.

Therefore, while potassium might not be a permanently bound cofactor, it absolutely fulfills the role of a cofactor in activating pyruvate kinase.

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