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What is a normal CSF level?

Published in CSF Analysis 1 min read

A normal cerebrospinal fluid (CSF) level depends on the specific component being measured. Here's a breakdown of normal ranges for key CSF constituents:

Normal CSF Values

Component Normal Range Units
Total Protein 15 to 60 mg/dL
Gamma Globulin 3 to 12 % of total protein
Glucose 50 to 80 (or > 2/3 of blood sugar) mg/dL

Explanation of Key Components:

  • Total Protein: This measures the overall protein concentration in the CSF. Elevated levels can indicate inflammation, infection, or other neurological disorders.

  • Gamma Globulin: This is a specific type of protein, and an increased percentage can be associated with immune-related conditions affecting the central nervous system.

  • Glucose: CSF glucose levels are usually compared to blood glucose levels. Low CSF glucose in relation to blood glucose can suggest infection (bacteria or fungi consume glucose).

Important Considerations:

  • These ranges are general guidelines, and specific laboratory values may vary slightly between institutions. Always interpret CSF results in conjunction with a patient's clinical presentation and other diagnostic findings.
  • A doctor is needed to properly interpret CSF lab results.

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