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How is CSF formed?

Published in CSF Formation 1 min read

Cerebrospinal fluid (CSF) is primarily formed within the brain's ventricles.

CSF Production Sites

Most CSF is produced by specialized structures known as the choroid plexuses. These intricate networks of capillaries and epithelial cells reside within the brain's ventricular system.

  • The choroid plexus is primarily located:
    • On the walls of the lateral ventricles.
    • On the roofs of the third ventricle.
    • On the roofs of the fourth ventricle.


Ependymal Cells Contribution

In addition to the choroid plexus, the ependymal cells that line the ventricles also contribute to CSF production, although in smaller amounts.


Summary of CSF Production

Structure Role in CSF Production Location
Choroid Plexus Major production site Ventricle walls and roofs
Ependymal Cells Minor production Lining of ventricles


Key Processes in CSF Formation:

  • Filtration and Secretion: The choroid plexus filters blood plasma and actively secretes specific components into the ventricles to form CSF.
  • Active Transport: Specialized cells in the choroid plexus transport ions and other substances to create the distinct composition of CSF.


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