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What happens if cortisol is high?

Published in Cushing syndrome 2 mins read

High cortisol levels over a prolonged period can lead to a condition called Cushing syndrome. This occurs when the body produces too much cortisol for an extended time.

Symptoms of high cortisol levels include:

  • Weight gain: Notably around the midsection and upper back, often accompanied by slender arms and legs.
  • Rounding of the face: This is due to fat deposition in the facial area.
  • Fatty deposits between the shoulder blades: This creates a characteristic "buffalo hump".
  • Purple or pink stretch marks on the skin.
  • Acne.
  • Thinning skin.
  • High blood pressure.
  • Bone loss.
  • Type 2 diabetes.

Causes of high cortisol levels:

  • Tumors: These can be located in the pituitary gland, which controls cortisol production, or in the adrenal glands, which produce cortisol.
  • Medications: Some medications, such as corticosteroids, can cause high cortisol levels.
  • Overproduction by the body: This can occur due to unknown causes or certain medical conditions.

Treatment for high cortisol levels:

  • Surgery: To remove tumors that are causing the overproduction of cortisol.
  • Medications: To block the production of cortisol or to suppress the pituitary gland's production of ACTH, the hormone that stimulates cortisol production.
  • Radiation therapy: To shrink tumors that are causing the overproduction of cortisol.

Note: High cortisol levels can have serious health consequences, so it is important to seek medical attention if you experience any of the symptoms.

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