Cytokine Release Syndrome (CRS) can be triggered by an overaggressive immune response to infections or certain immunotherapies.
Understanding Cytokine Release Syndrome (CRS)
CRS, sometimes referred to as cytokine storm or cytokine-associated toxicity, results from the immune system's excessive reaction. This overreaction leads to the release of a large amount of cytokines into the body.
Causes of CRS
According to the reference material, common causes of CRS include:
- Infections: The immune system responds too aggressively to the infection.
- Immunotherapy: Certain types of immunotherapy, such as CAR T-cell therapy, can induce CRS.