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What is the chemical composition of dentin?

Published in Dentistry 2 mins read

Dentin is primarily composed of inorganic hydroxyapatite, organic matter (mainly collagen), and water.

Detailed Composition of Dentin

Dentin's chemical composition can be broken down into the following components:

  • Inorganic Component (Approximately 70% by weight):

    • Hydroxyapatite: The main inorganic component is hydroxyapatite, a crystalline form of calcium phosphate. Its chemical formula is Ca10(PO4)6(OH)2. This provides dentin with its hardness and rigidity.
  • Organic Component (Approximately 20% by weight):

    • Collagen: Primarily Type I collagen constitutes the major organic matrix. This collagen provides the framework upon which hydroxyapatite crystals are deposited.
    • Non-Collagenous Proteins: Various other proteins, including proteoglycans, glycoproteins (like dentin sialoprotein and dentin phosphoprotein), and growth factors, are present in smaller quantities and play essential roles in dentin formation and mineralization.
  • Water (Approximately 10% by weight):

    • Water is present within the dentinal tubules and the organic matrix, contributing to the overall structure and function of dentin.

Table Summarizing Dentin Composition

Component Percentage (by weight)
Inorganic (Hydroxyapatite) ~70%
Organic (Collagen, etc.) ~20%
Water ~10%

In summary, dentin's composition reflects a highly organized arrangement of mineral and organic components, resulting in a tissue that is both hard and slightly elastic, providing support for the enamel.

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