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Which collagen is absent in enamel?

Published in Dentistry 1 min read

Type VII collagen is absent in enamel. The reference indicates that type VII collagen, encoded by the COL7 gene, is a major component of anchoring fibrils in the epidermal basement membrane zone and that mutations in this gene can cause defective tooth enamel formation due to poor ameloblast differentiation. This implies that while other types of collagen may be present in enamel, Type VII is not a normal component.

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