NME in dermatology stands for Necrolytic Migratory Erythema, a distinctive skin rash often linked to glucagonoma.
Understanding Necrolytic Migratory Erythema (NME)
Necrolytic migratory erythema (NME) is significant in dermatology because it often signals an underlying systemic issue, most notably glucagonoma. Here's a breakdown:
- Definition: NME is a specific type of skin rash.
- Association: According to references, it is most frequently associated with glucagonoma. Glucagonoma is an alpha-cell tumor of the pancreatic islets.
- Paraneoplastic Syndrome: NME is a component of glucagonoma syndrome, which is a paraneoplastic syndrome that includes the triad of diabetes mellitus, NME, and weight loss.
In essence, identifying NME in a dermatological examination can lead to the discovery and treatment of a potentially serious underlying condition like glucagonoma.