While calluses are most commonly caused by repeated friction or pressure, certain diseases and conditions can also contribute to their formation. The most notable one is Pachyonychia Congenita (PC).
Here's a breakdown:
Pachyonychia Congenita (PC)
- Definition: PC is a rare genetic disorder affecting the skin and nails.
- Calluses as a Symptom: A key symptom of PC is the development of painful calluses, especially on the soles of the feet. These calluses can make walking extremely difficult, sometimes requiring the use of assistive devices like canes, crutches, or wheelchairs.
- Other Symptoms: PC also typically involves thickened nails.
It's important to note that calluses themselves are often a result of mechanical factors (friction and pressure) and are not always indicative of an underlying disease. However, persistent or unusually severe calluses, especially when accompanied by other symptoms, should be evaluated by a healthcare professional to rule out underlying conditions like PC.
