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Which Blood Test for Pimples?

Published in Dermatology 3 mins read

The specific blood tests for pimples (acne) depend on the suspected underlying cause, but common tests include hormone level assessments and lipid profiles.

While there isn't one single "pimples blood test," doctors often order blood tests to investigate potential hormonal imbalances or other underlying conditions contributing to acne, especially in cases of severe or persistent acne. Here's a breakdown of common tests:

  • Hormone Level Tests:

    • Sex Hormone-Binding Globulin (SHBG): Low levels of SHBG can lead to increased levels of free androgens, which can contribute to acne.
    • Dehydroepiandrosterone Sulfate (DHEA-S): Elevated DHEA-S is often seen in women with acne.
    • Testosterone (Total and Free): High levels of testosterone can stimulate sebum production, leading to acne.
    • Androstenedione: Another androgen hormone that may be checked.
    • Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH): These hormones are often tested in women to assess ovarian function, particularly if there are signs of polycystic ovary syndrome (PCOS).
    • Prolactin: Elevated prolactin levels can sometimes contribute to hormonal imbalances.
  • Lipid Profile: This test measures cholesterol and triglyceride levels. While not directly related to causing acne, it's sometimes ordered alongside hormonal tests as part of a broader metabolic evaluation, especially if the patient has other risk factors or symptoms.

  • Other Tests (less common, depending on the situation):

    • Glucose and Insulin: To assess for insulin resistance, which can exacerbate hormonal imbalances.
    • Inflammatory Markers (e.g., C-reactive protein or CRP): Elevated inflammatory markers may be relevant in severe or inflammatory acne.

Why are these tests done?

Acne can be influenced by various factors, including:

  • Hormonal Imbalances: Androgens, in particular, play a significant role in sebum production, which contributes to clogged pores and acne development.
  • Inflammation: Inflammation plays a key role in acne formation.
  • Genetics: A predisposition to acne can run in families.
  • Other Underlying Conditions: Certain medical conditions, like PCOS, can manifest with acne as a symptom.

In summary: There's no single "pimples blood test." Doctors order specific blood tests based on your individual symptoms and medical history to identify potential underlying causes of your acne, such as hormonal imbalances or other contributing factors. Common tests include hormone level assessments (SHBG, DHEA-S, testosterone, etc.) and lipid profiles.

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