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How does the body produce stomach acid?

Published in Digestive Physiology 2 mins read

Stomach acid, crucial for digestion, is produced by specialized cells in the stomach lining.

The Key Players: Parietal Cells

The primary cells responsible for stomach acid production are called parietal cells. These cells are located in the proximal two-thirds (body) of the stomach. Here's a closer look at their function:

  • Secretion: Parietal cells actively secrete hydrochloric acid (HCl), the main component of stomach acid.
  • Location: These cells are strategically positioned within the gastric glands of the stomach lining.

Why is Stomach Acid Important?

Gastric acid plays several vital roles in the digestive process:

  • Optimal pH for Enzymes: It creates the acidic environment required for the digestive enzyme pepsin to break down proteins. Gastric lipase also functions optimally in this low pH.
  • Stimulates Bicarbonate Secretion: Gastric acid also triggers the pancreas to release bicarbonate, a base that neutralizes the acidity from the stomach further down in the digestive system.

Summary of Stomach Acid Production

Process Description
Cell Type Parietal Cells
Location Proximal two-thirds (body) of the stomach lining
Acid Secreted Hydrochloric Acid (HCl)
Enzyme Activation Provides the required low pH for pepsin and gastric lipase
Other Effects Stimulates pancreatic bicarbonate secretion.

In essence, specialized parietal cells in the stomach lining are the direct source of stomach acid (hydrochloric acid). This acid is essential for creating an optimal environment for digestion and enzyme activity.

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