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What drugs cause hepatitis?

Published in Drug-Induced Hepatitis 3 mins read

Certain medications can indeed cause drug-induced hepatitis, a condition where the liver becomes inflamed due to a reaction to a drug or other substance. Here's a breakdown of some known culprits:

Medications That Can Lead to Hepatitis

The medications listed below have been identified as potential causes of hepatitis. It's important to remember that not everyone who takes these drugs will develop hepatitis; the risk varies based on individual factors.

Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

  • Description: These are common over-the-counter pain and fever relievers.
  • Examples: Aspirin, ibuprofen, and naproxen are all examples of NSAIDs.
  • Reference: As the reference confirms, "Aspirin and over-the-counter pain and fever medicines (NSAIDs or nonsteroidal anti-inflammatory medicines)" are included in the list of medications that can cause hepatitis.

Anabolic Steroids

  • Description: Man-made hormones similar to testosterone.
  • Use: Sometimes abused by athletes to build muscle mass or used for certain medical conditions under prescription.
  • Reference: According to the provided references, "Anabolic steroids, man-made medicines that are like the male sex hormone testosterone" are identified as a potential cause of hepatitis.

Antibiotics

  • Description: Medications used to treat bacterial infections.
  • Variety: A wide range of antibiotics exists, and some may be more likely to cause liver issues than others.
  • Reference: As the provided reference indicates, "Some medicines used to treat bacterial infections (antibiotics)" can contribute to hepatitis.

Oral Contraceptives

  • Description: Commonly known as birth control pills.
  • Hormonal Effects: They can affect liver function in certain individuals.
  • Reference: The references mention that "Birth control pills (oral contraceptives)" are another class of drugs that can potentially cause hepatitis.

Understanding Drug-Induced Hepatitis

  • Mechanism: Drug-induced hepatitis happens when the liver gets damaged by a drug or its byproducts as it tries to process it.
  • Symptoms: Symptoms can vary from mild (such as fatigue and mild jaundice) to severe (such as abdominal pain, dark urine, and liver failure).
  • Diagnosis: Diagnosis often involves blood tests and liver function evaluations, as well as taking into account a person's medication history.
  • Treatment: Management typically involves stopping the causative medication and providing supportive care.

Important Notes

  • Individual Variation: Not everyone taking these medications will develop hepatitis.
  • Consult a Doctor: Always consult with a healthcare provider before starting or stopping any medication.
  • Transparency: It's crucial to provide a complete medical and medication history to your doctor.
  • Monitoring: Regular monitoring may be required if you are on a medication known to cause hepatitis.

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