Certain medications can cause jaundice as a side effect, primarily through drug-induced liver injury. Here's a list of some drugs associated with this condition, based on the provided reference:
Several drugs can cause jaundice by causing cholestatic liver injury. These include, but aren't limited to:
- Chlorpromazine
- Ciprofloxacin
- Ofloxacin
- Cimetidine
- Phenytoin
- Naproxen
- Captopril
- Erythromycin
- Azithromycin
- Dicloxacillin
- Amoxicillin-clavulanic acid
| Drug | Class | Mechanism (Simplified) |
|---|---|---|
| Chlorpromazine | Antipsychotic | Can disrupt bile flow within the liver. |
| Ciprofloxacin/Ofloxacin | Fluoroquinolone Antibiotics | May cause liver inflammation leading to jaundice. |
| Cimetidine | H2 Receptor Antagonist | Possible liver cell damage or bile duct obstruction. |
| Phenytoin | Anticonvulsant | Hypersensitivity reactions affecting the liver. |
| Naproxen | NSAID (Nonsteroidal Anti-Inflammatory) | Liver inflammation. |
| Captopril | ACE Inhibitor | Cholestatic or hepatocellular damage. |
| Erythromycin/Azithromycin | Macrolide Antibiotics | Intrahepatic cholestasis (bile build-up in the liver). |
| Dicloxacillin | Penicillin Antibiotic | Allergic reaction leading to liver inflammation. |
| Amoxicillin-clavulanic acid | Penicillin Antibiotic | Cholestatic jaundice, where bile flow is impaired. |
It is important to note that not everyone who takes these medications will develop jaundice. Jaundice is often caused by other underlying diseases. If you experience yellowing of the skin or eyes while taking any medication, consult a doctor.
