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Can I Take Vitamin B12 With Pantoprazole?

Published in Drug Interactions & Supplements 2 mins read

Yes, you can take vitamin B12 with pantoprazole, and it's often recommended to do so to prevent vitamin B12 deficiency. The combined usage ensures the prevention of vitamin B12 deficiency (31-May-2023).

Understanding the Interaction (and lack thereof)

  • Pantoprazole's effect: Pantoprazole is a proton pump inhibitor (PPI) that reduces stomach acid production.
  • Vitamin B12 absorption: Stomach acid is needed to release vitamin B12 from food so it can be properly absorbed. Reduced stomach acid, caused by pantoprazole, could potentially lead to B12 deficiency over time.
  • Supplementing is key: Taking a vitamin B12 supplement alongside pantoprazole bypasses the need for stomach acid in the absorption process, mitigating the risk of deficiency.

Why Consider Taking Vitamin B12 with Pantoprazole?

Here's a breakdown of why taking vitamin B12 with pantoprazole is often recommended:

  • Prevent Deficiency: Long-term use of pantoprazole can impair vitamin B12 absorption, leading to deficiency.
  • Maintain Energy Levels: Vitamin B12 is crucial for energy production. Deficiency can cause fatigue and weakness.
  • Support Nerve Function: B12 is essential for healthy nerve function. Deficiency can lead to neurological issues.

Practical Insights and Solutions

  • Consider Sublingual B12: Sublingual B12 (under the tongue) bypasses the stomach acid requirement altogether.
  • Regular Monitoring: If you're on long-term pantoprazole, have your B12 levels checked regularly by your doctor.
  • Dietary Sources: While supplementing is helpful, also focus on B12-rich foods like meat, fish, eggs, and dairy.

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