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Why is it called heparin?

Published in Drug Nomenclature 2 mins read

Heparin gets its name from the Greek word for liver, because it was initially extracted from dog liver cells.

Understanding the Origin of Heparin's Name

Heparin's journey from a biological substance to a widely used medication has a fascinating origin, rooted in its discovery and the source from which it was first isolated. Here's a breakdown:

  • Discovery: Heparin was discovered in 1916 by Jay McLean and William Henry Howell.
  • Initial Isolation: The substance was first isolated from dog liver cells.
  • Greek Root: The name "heparin" is derived from the Greek word ἧπαρ (hēpar), meaning "liver." The suffix "-in" is a common ending used for substances of biological origin. Therefore, hepar + -in = heparin.

Key Takeaways

  • The name "heparin" directly reflects its initial source, highlighting the importance of biological origins in pharmaceutical naming.
  • The use of Greek roots is common in scientific terminology, providing a consistent method for nomenclature.
  • The discovery and naming of heparin laid the foundation for its development and use in medical treatments, from its first clinical trials in 1935, to the present day.

In summary, heparin's name serves as a direct reminder of where this crucial anticoagulant was first found—the liver.

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