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What is a Positive Drug Test?

Published in Drug Testing 2 mins read

A positive drug test indicates the presence of drugs in a person's system at levels suggesting drug use or misuse.

Understanding Positive Drug Test Results

When a drug test comes back positive, it doesn't automatically confirm drug use definitively. It means that the test detected one or more drugs above the established cutoff levels. According to the provided reference, one or more drugs were found in amounts that suggest drug use or misuse. However, due to the possibility of false positives, further testing is usually required.

Key Aspects of a Positive Drug Test:

  • Detection Thresholds: Drug tests have specific cutoff levels. A positive result occurs when the concentration of a drug or its metabolites exceeds these levels.
  • Confirmation Testing: Initial positive results are typically followed by a more sensitive and specific confirmatory test, often using gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-mass spectrometry (LC-MS), to rule out false positives. The reference confirms that positive tests require follow-up testing because they may be wrong (false positives). The follow-up test is usually a test that provides more accurate results.
  • Factors Influencing Results: Various factors can influence drug test results, including:
    • Medications (prescription and over-the-counter)
    • Foods
    • Cross-reactivity with other substances

Why Follow-Up Testing is Crucial

Follow-up or confirmation testing is a critical step to ensure the accuracy of drug test results. False positives can arise from various sources, leading to incorrect accusations and potential consequences. The reference also indicates that Positive tests require follow-up testing because they may be wrong (false positives).

Examples of Scenarios Requiring Drug Tests

Drug tests are commonly used in various settings:

  • Employment: Many employers require drug tests as part of the hiring process or for random testing during employment.
  • Sports: Athletes are often subject to drug testing to ensure fair competition.
  • Legal/Forensic: Drug tests are used in criminal investigations and legal proceedings.
  • Medical: In some cases, drug tests may be used to monitor patients' medication adherence or to diagnose substance abuse issues.

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