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What deficiency causes hyponatremia?

Published in Electrolyte Imbalance 2 mins read

Hyponatremia isn't caused by a deficiency of something; it's defined as having a low concentration of sodium in the blood. However, several underlying conditions or factors can lead to hyponatremia.

Hyponatremia, by definition, is a condition in which the sodium level in the blood is abnormally low (below 135 mEq/L). While it's not caused by a "deficiency" in the traditional sense, it arises from an imbalance between sodium and water in the body. It indicates either a relative excess of water or a relative loss of sodium.

Here's a breakdown of the more common causes:

  • Excess Water Intake: Drinking too much water, especially during endurance activities, can dilute the sodium concentration in the blood.
  • Hormonal Imbalances:
    • SIADH (Syndrome of Inappropriate Antidiuretic Hormone Secretion): This condition causes the body to retain too much water, diluting sodium levels. SIADH can be triggered by certain medications, lung diseases, tumors, and nervous system disorders.
    • Adrenal Insufficiency (Addison's Disease): A deficiency in cortisol and aldosterone can lead to sodium loss and water retention.
    • Hypothyroidism: Underactive thyroid can sometimes contribute to hyponatremia.
  • Kidney Problems: Kidney disorders can impair the kidneys' ability to regulate sodium and water balance.
  • Certain Medications: Diuretics (water pills) are a common cause, as they promote sodium excretion through the kidneys. Other medications can also interfere with hormonal regulation or kidney function, contributing to hyponatremia.
  • Heart Failure: Heart failure can cause fluid retention, which dilutes sodium levels.
  • Liver Cirrhosis: Liver disease can lead to fluid accumulation in the abdomen (ascites), which can dilute sodium.
  • Severe Vomiting or Diarrhea: Excessive fluid and electrolyte loss can deplete sodium levels.
  • Burns: Extensive burns can lead to significant sodium losses through the damaged skin.
  • Some Rare Causes: Polydipsia (excessive thirst), beer potomania (excessive beer consumption)
    In summary, while hyponatremia itself isn't a "deficiency," it results from various conditions that disrupt the balance of sodium and water in the body. These can range from excessive water intake to hormonal imbalances and kidney problems.

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