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What are Islet Cells?

Published in Endocrine Cells 2 mins read

Islet cells are specialized cells within the pancreas that play a crucial role in regulating blood sugar levels. These cells are also known as endocrine pancreas cells or islet of Langerhans cells.

Key Functions of Islet Cells

  • Hormone Production: The primary function of islet cells is to produce and secrete hormones directly into the bloodstream.
    • Insulin: This hormone helps lower blood glucose levels by allowing cells to take up glucose from the blood for energy.
    • Glucagon: This hormone works to increase blood glucose levels by signaling the liver to release stored glucose.


Understanding the Role in Blood Sugar Regulation

Hormone Effect on Blood Glucose Produced By
Insulin Decreases Islet cells
Glucagon Increases Islet cells


The balance between insulin and glucagon secretion is critical for maintaining stable blood sugar levels. When this balance is disrupted, it can lead to conditions like diabetes. For example:

  • Type 1 Diabetes: Occurs when the islet cells that produce insulin are destroyed, resulting in an inability to lower blood sugar.
  • Type 2 Diabetes: Occurs when cells become resistant to insulin, and the islet cells may not produce enough insulin.


Importance in Human Health

The proper functioning of islet cells is essential for overall health. These tiny cells are responsible for the vital task of regulating glucose, which is the primary source of energy for the body. Dysfunction or damage to these cells leads to various health problems related to metabolism.


In summary, islet cells are vital components of the pancreas that produce and release hormones, particularly insulin and glucagon, that control blood glucose levels.

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