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Where is glucagon converted?

Published in Endocrine System 1 min read

Glucagon is not converted. Instead, glucagon acts as a signaling molecule that primarily causes the liver to convert stored glycogen into glucose.

Glucagon, a peptide hormone released by the alpha cells of the pancreas, plays a crucial role in regulating blood glucose levels. When blood glucose levels drop too low, the pancreas releases glucagon. Glucagon then travels to the liver, where it triggers a series of biochemical reactions.

Here's a breakdown of glucagon's action in the liver:

  • Glycogenolysis: Glucagon stimulates the breakdown of glycogen (the stored form of glucose) into glucose. This newly formed glucose is then released into the bloodstream, raising blood sugar levels.

  • Gluconeogenesis: Glucagon also promotes gluconeogenesis, the synthesis of glucose from non-carbohydrate sources, such as amino acids and glycerol. This process further contributes to increasing blood glucose levels.

In summary, glucagon doesn't undergo conversion itself. It initiates the conversion of glycogen to glucose primarily in the liver, ultimately increasing blood glucose concentration.

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