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Which Cell Produces Glucagon?

Published in Endocrine System 2 mins read

The alpha cells of the pancreas produce glucagon.

Understanding Glucagon and Its Source

Glucagon is a peptide hormone essential for regulating blood glucose levels. When blood sugar levels drop too low, glucagon is released to raise them back to normal. This hormone is specifically produced by a particular type of cell within the pancreas called the alpha cell.

Alpha Cells: The Glucagon Factories

  • Location: Alpha cells are found in the islets of Langerhans within the pancreas. These islets are clusters of endocrine cells that produce various hormones.
  • Function: They are responsible for synthesizing and secreting glucagon into the bloodstream.
  • Stimulus: Alpha cells release glucagon when blood glucose levels are low, typically between meals or during fasting.

Why Glucagon Production is Important

Glucagon plays a vital role in maintaining glucose homeostasis. When blood sugar is low, glucagon works by:

  1. Stimulating Glycogenolysis: It encourages the breakdown of glycogen (stored glucose) in the liver, releasing glucose into the blood.
  2. Promoting Gluconeogenesis: It supports the liver to synthesize new glucose molecules from other sources, such as amino acids.

Quick Summary

Cell Type Hormone Produced Function
Alpha Cells Glucagon Raises blood glucose levels when low.

In conclusion, the specific cells responsible for producing glucagon are the alpha cells of the pancreas.

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