Irregular endometrium, often manifesting as endometrial hyperplasia, primarily results from an imbalance of estrogen and progesterone. This imbalance is frequently associated with factors that disrupt regular ovulation and progestin production, as mentioned in the reference.
Understanding the Imbalance
Normally, estrogen promotes endometrial growth, while progesterone regulates this growth and causes the shedding of the endometrium (menstruation). When this balance is disturbed, particularly with excessive estrogen relative to progesterone, the endometrium may become irregular.
Factors Contributing to Irregular Endometrium:
Several factors can contribute to this hormonal imbalance:
- Irregular Menstrual Periods: This is explicitly stated in the reference.
- When menstrual cycles are irregular, ovulation might not occur consistently, reducing progesterone production and leading to excessive estrogen dominance.
- Obesity: Excess body fat can produce estrogen, further contributing to the estrogen-progesterone imbalance and impacting the endometrium as described in the provided reference.
- Obesity, in particular, is related to excess estrogen production.
- Polycystic Ovary Syndrome (PCOS): Women with PCOS often experience irregular ovulation and hormonal imbalances, including reduced progestin levels, as mentioned in the reference.
- PCOS is characterized by irregular ovulation, which can lead to less progesterone.
Here's a summarized view:
| Factor | Effect on Hormones | Impact on Endometrium |
|---|---|---|
| Irregular Menstrual Periods | Inconsistent ovulation, reduced progestin | Irregular endometrial growth |
| Obesity | Increased estrogen production | Potential for hyperplasia |
| Polycystic Ovary Syndrome | Reduced progestin due to ovulation problems | Higher risk of irregular endometrium |
What to Do?
If you suspect you have an irregular endometrium, consult a healthcare professional. They can diagnose the condition through tests like endometrial biopsies and recommend appropriate management strategies. These strategies may include hormonal therapy to restore balance, lifestyle changes, and if necessary, surgery.
