Endothelial cells secrete a variety of substances, often in a polarized manner, meaning they release different substances from different sides of the cell. According to the provided reference, specific examples include antithrombin III and plasminogen activator being released into the vascular lumen, while collagen IV and V, and laminin are largely secreted from the basolateral side.
| Substance Secreted | Location of Secretion |
|---|---|
| Antithrombin III | Vascular lumen |
| Plasminogen activator | Vascular lumen |
| Collagen IV | Basolateral side |
| Collagen V | Basolateral side |
| Laminin | Basolateral side |
