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What is hypopyon in the eye?

Published in Eye Condition 3 mins read

Hypopyon is the accumulation of white blood cells in the eye's anterior chamber, indicating a serious issue. It is crucial to understand what it is, its symptoms, and the importance of seeking immediate medical attention.

Defining Hypopyon

A hypopyon (hye-POE-pee-on) is the accumulation of white blood cells that form a whitish layer of fluid in the lower portion of the eye's anterior chamber (front part), as stated in the reference. This collection of inflammatory cells is usually visible without any special equipment.

Key Characteristics:

  • Appearance: It looks like a white or yellowish fluid layer settled at the bottom of the cornea.
  • Composition: Made up of white blood cells.
  • Location: Found in the anterior chamber of the eye.
  • Visibility: Generally visible without magnification.

Significance

A hypopyon is a sign of significant intraocular inflammation, and its presence signifies a serious underlying condition. According to the reference, it indicates severe inflammation or infection and requires urgent evaluation.

Conditions Associated with Hypopyon:

The presence of hypopyon can be indicative of several underlying conditions:

  • Infections: Bacterial, fungal, or viral infections of the cornea or inside the eye.
  • Uveitis: Inflammation of the middle layer of the eye (uvea).
  • Endophthalmitis: A severe inflammation of the interior of the eye, often due to infection.
  • Trauma: Injury to the eye.
  • Certain systemic diseases: Including Behcet's disease.

Symptoms

While the hypopyon itself is a visible sign, other symptoms can accompany it, helping to identify the underlying cause. These may include:

  • Eye pain.
  • Redness of the eye.
  • Blurred vision or vision loss.
  • Sensitivity to light (photophobia).
  • Tearing.

When to Seek Medical Attention

As the reference mentions, hypopyon requires urgent evaluation. It should be considered an emergency because the conditions causing it can lead to serious complications, including vision loss.

Diagnosis and Treatment

A comprehensive eye examination is essential to diagnose the cause of the hypopyon. This may involve:

  • Visual acuity testing.
  • Slit-lamp examination.
  • Measuring intraocular pressure.
  • Microbial cultures (if infection is suspected).

Treatment depends on the underlying cause and may include:

  • Antibiotics or antifungals: For infections.
  • Steroid eye drops: To reduce inflammation.
  • Pain medication: To alleviate discomfort.
  • Surgery: In severe cases, such as endophthalmitis.

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