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What is PCV in the eye?

Published in Eye disease 2 mins read

PCV in the eye refers to Polypoidal Choroidal Vasculopathy, a specific type of eye condition affecting the macula. More specifically, Polypoidal Choroidal Vasculopathy (PCV) is an exudative maculopathy characterized by multiple recurrent serosanguineous retinal pigment epithelial detachments (PED), according to reference materials.

Understanding Polypoidal Choroidal Vasculopathy (PCV)

PCV shares similarities with neovascular age-related macular degeneration (AMD) in its morphological characteristics. Let's break down the key components:

  • Exudative Maculopathy: This means that the condition involves fluid leakage in the macula, the central part of the retina responsible for sharp, detailed vision.
  • Serosanguineous Retinal Pigment Epithelial Detachments (PED): This refers to the separation of the retinal pigment epithelium (RPE) from the underlying tissue, accompanied by fluid that is both serous (clear, yellowish) and sanguineous (containing blood). These detachments are recurrent, meaning they happen multiple times.
  • Polypoidal: Refers to the presence of polyp-like structures in the choroidal vessels, which are abnormal blood vessels located beneath the retina. These polypoidal lesions are a defining characteristic of PCV.

Key Features of PCV

To better understand PCV, consider these key features:

  • Abnormal blood vessels develop in the choroid.
  • These vessels can leak fluid and blood, leading to swelling and damage to the macula.
  • The presence of polyp-like structures distinguishes PCV from typical AMD.
  • Recurrent detachments can cause progressive vision loss.

PCV vs. AMD

While PCV shares similarities with neovascular AMD, there are distinctions:

Feature PCV Neovascular AMD
Defining feature Polypoidal lesions New blood vessel growth (choroidal neovascularization)
Primary Location Choroid Choroid
Fluid Leakage Common Common
Treatment Approach Similar but may require specific interventions Similar but may require specific interventions

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