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What is ECC eye?

Published in Eye Health 2 mins read

ECC in the context of eye health refers to Endothelial Cell Count, a measurement of the cells on the back surface of the cornea. This is an important diagnostic test, particularly for individuals with corneal disease.

Understanding Endothelial Cell Count (ECC)

Here's a detailed look at ECC:

  • Definition: Endothelial Cell Count (ECC) is the measurement of the number of endothelial cells that line the posterior (back) surface of the cornea.
  • Significance: These cells are crucial for maintaining corneal clarity. They pump fluid out of the cornea, preventing it from becoming swollen and opaque.
  • Clinical Application: ECC is primarily used in patients with corneal disease to assess the health and function of the corneal endothelium.

Why is ECC Important?

A healthy endothelium is vital for clear vision. Damage or a significant reduction in endothelial cell count can lead to corneal edema (swelling), resulting in blurred vision and discomfort.

Here's a breakdown of why monitoring ECC is important:

  • Corneal Health Assessment: ECC provides valuable information about the overall health of the cornea.
  • Diagnosis and Monitoring: It aids in the diagnosis and monitoring of various corneal diseases, such as Fuchs' dystrophy.
  • Surgical Planning: ECC is crucial before corneal surgeries like cataract surgery or corneal transplants. A low ECC may indicate a higher risk of complications.

How is ECC Measured?

ECC is measured using specialized instruments such as:

  • Specular Microscopes: These instruments provide a non-invasive way to image and count the endothelial cells.
  • Confocal Microscopes: Offer higher resolution images and can be used to assess the morphology (shape) of the cells in addition to their count.

Example Scenario

Imagine a patient scheduled for cataract surgery. Their ophthalmologist orders an ECC test. If the ECC is low, it suggests that the cornea might be vulnerable and unable to handle the stress of surgery. In this case, the surgeon might modify the surgical approach or consider additional protective measures.

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