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What organs are affected by fasting?

Published in Fasting Physiology 1 min read

Fasting primarily affects the liver initially, but prolonged fasting impacts multiple organs as the body adapts to energy deprivation.

Initial Impact: The Liver's Role

  • Glycogen Depletion: During the first 24 hours of fasting, the liver plays a crucial role in maintaining blood glucose levels by breaking down stored glycogen. According to the provided information, most glycogen is stored in the liver.
  • Blood Glucose Maintenance: The liver is central to maintaining blood glucose during this initial fasting period. After about 24 hours, glycogen stores become depleted.

Long-Term Effects and Other Organs Involved

Once glycogen stores are depleted, the body shifts to utilizing other energy sources, leading to effects on additional organs and systems:

  • Adipose Tissue: The body starts utilizing energy stores from adipose tissue
  • Protein Stores: The body starts utilizing energy stores from protein stores

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