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What is the physiology of fat storage?

Published in Fat Physiology 3 mins read

Fat storage, or lipogenesis, is the process by which the body stores excess energy in the form of fat. Here's how it works:

The Role of Adipocytes

The primary cells responsible for fat storage are adipocytes, also known as fat cells. According to references, these cells are specifically designed to store fat.

  • Location: Adipocytes are mostly located:
    • Just under the skin throughout the body (subcutaneous fat).
    • Around vital organs (visceral fat), offering protection.

How Fat is Stored

  1. Dietary Fat: When we consume fats (lipids), they are broken down into smaller molecules, such as fatty acids and glycerol, during digestion.
  2. Triglycerides Formation: These molecules are then reassembled within the body into triglycerides.
  3. Adipocyte Uptake: Triglycerides are transported to adipocytes, where they are taken up and stored as lipid droplets.
  4. Storage: Inside the adipocyte, triglycerides are packaged and stored within the cell's cytoplasm.
  5. Expansion: When more energy is available than needed, the size and number of these adipocytes can increase to accommodate more triglycerides.

Types of Fat Storage

  • Subcutaneous Fat: This is the fat stored directly beneath the skin, which can be measured by skinfold calipers. It is the most abundant type of fat storage.
  • Visceral Fat: Found deep inside the abdomen surrounding vital organs, and often associated with higher health risks. It is more metabolically active than subcutaneous fat.

Fat Storage Regulation

The processes of fat storage are influenced by various factors:

  • Hormones: Insulin promotes fat storage, while hormones like adrenaline can trigger fat release.
  • Enzymes: Lipoprotein lipase helps to uptake triglycerides, while hormone-sensitive lipase facilitates the breakdown of fat for energy.
  • Energy Balance: When we consume more calories than we burn, the excess is converted into and stored as fat.

Practical Considerations

Understanding fat storage physiology can inform our health practices:

  • Diet: Consuming a balanced diet is crucial to regulate fat storage and prevent excess accumulation.
  • Exercise: Regular physical activity helps in burning stored fat and improves metabolic health.
  • Metabolic Health: Knowing that visceral fat is more metabolically active than subcutaneous fat means focusing on losing visceral fat is often beneficial.

Summary

In short, fat storage involves the conversion of excess dietary fat into triglycerides, which are stored inside adipocytes located under the skin and around organs. Understanding the physiological processes behind fat storage can help us make more informed decisions about our diet and lifestyle.

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