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What is AFC Analysis?

Published in Fertility Testing 2 mins read

AFC analysis refers to the Antral Follicle Count (AFC), a crucial assessment used to evaluate a woman's ovarian reserve and predict the potential success of fertility treatments, like egg freezing. Essentially, it's a count of the small, fluid-filled sacs (antral follicles) visible in the ovaries during a transvaginal ultrasound.

Here's a breakdown of AFC analysis:

  • What are Antral Follicles? Antral follicles are small, fluid-filled sacs in the ovaries that contain immature eggs. They are visible on ultrasound during the early part of a woman's menstrual cycle (typically days 2-5).

  • How is AFC Measured? An AFC is determined through a transvaginal ultrasound. A fertility specialist will carefully count the number of antral follicles in both ovaries.

  • Why is AFC Important?

    • Ovarian Reserve Assessment: The number of antral follicles roughly correlates with the number of eggs remaining in a woman's ovaries (her ovarian reserve). A higher AFC generally indicates a better ovarian reserve.
    • Predicting Fertility Treatment Success: AFC is a key factor in predicting how well a woman will respond to ovarian stimulation during fertility treatments like IVF (in vitro fertilization) or egg freezing.
    • Dosage of Stimulation Medications: The AFC helps doctors determine the appropriate dosage of medication needed for ovarian stimulation.
    • Diagnosing Ovarian Conditions: An abnormally high AFC can be indicative of conditions like Polycystic Ovary Syndrome (PCOS).
  • Interpreting AFC Results:

    • There's no single "normal" AFC, as it varies with age.
    • Generally, a higher AFC is more desirable for fertility.
    • An AFC considered "low" for a woman's age may indicate diminished ovarian reserve (DOR).
    • Consult with a fertility specialist for a proper interpretation of your AFC results.
  • Factors Affecting AFC: Age is the primary factor affecting AFC. As a woman ages, her ovarian reserve naturally declines, leading to a lower AFC. Other factors can include genetics, lifestyle choices (like smoking), and certain medical conditions or treatments.

In summary, AFC analysis provides valuable information about a woman's reproductive potential by assessing her ovarian reserve. It's a vital tool in guiding fertility treatment decisions and setting realistic expectations.

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