The first stage of fibrosis involves the initial changes within the tissue structure. According to the provided reference, the first stage of fibrosis is an expansion of some portal areas, possibly with short, fibrous septa.
Here's a breakdown of the fibrosis stages mentioned in the reference:
Stage | Description |
---|---|
0 | Absence of fibrosis. |
1 | Expansion of some portal areas, possibly with short, fibrous septa. |
2 | Expansion of most portal areas, possibly with short, fibrous septa. |
3 | Expansion of portal areas with sporadic portal-to-portal bridging. |
Therefore, stage 1 represents the beginning of fibrosis, characterized by localized changes in the portal areas with early signs of fibrous tissue formation.