Yes, folic acid, particularly synthetic folate, can influence hormone levels, specifically progesterone.
Research suggests a correlation between higher intake of synthetic folate and increased luteal progesterone levels. A study indicated that women in the highest tertile of synthetic folate intake experienced, on average, 16.0% higher luteal progesterone levels compared to those in the lowest tertile. This implies that folic acid supplementation might have an impact on hormonal balance, especially concerning progesterone during the luteal phase of the menstrual cycle.
It's important to note that the research focuses on synthetic folate, often found in supplements and fortified foods, rather than folate naturally present in foods like leafy green vegetables.
| Aspect | Finding |
|---|---|
| Synthetic Folate | Higher intake associated with higher luteal progesterone levels. |
| Progesterone | Women with higher synthetic folate intake showed significantly increased levels. |
This suggests that the type of folate consumed might be a crucial factor in understanding its hormonal effects. Further research is needed to fully elucidate the mechanisms and potential long-term implications of synthetic folate on hormone regulation and overall health.
