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Can Eggs Cause High Eosinophils?

Published in Food Allergies 3 mins read

Yes, eggs can cause high eosinophils, particularly in the context of eosinophilic esophagitis.

Understanding Eosinophilic Esophagitis and Eosinophils

Eosinophilic esophagitis (EoE) is an inflammatory condition where eosinophils, a type of white blood cell, accumulate in the esophagus. This accumulation can cause various symptoms, including difficulty swallowing and food impaction. It is important to note that EoE is often a reaction to certain foods.

How Eggs Play a Role

According to the provided reference, egg protein is one of the more common triggers for the development of eosinophilic esophagitis [4]. This means that in susceptible individuals, consuming eggs can lead to an immune response that causes eosinophils to gather in the esophageal lining. The response can be mediated by both IgE and non-IgE mechanisms.

Other Triggers for Eosinophilic Esophagitis

While eggs are a common culprit, other foods can also trigger EoE. These include:

  • Milk
  • Wheat
  • Soy
  • Nuts
  • Seafood

It's worth noting that many people who react to eggs will not necessarily react to all of these other potential allergens.

How to Approach Suspected Egg-Related EoE

If you suspect that eggs are causing high eosinophils and symptoms of EoE, it's essential to consult a healthcare professional. They may recommend the following:

  1. Allergy Testing: To identify potential food triggers.
  2. Dietary Changes: Elimination of suspected foods (like eggs) under the guidance of a medical expert.
  3. Upper Endoscopy with Biopsy: To confirm the diagnosis of EoE and evaluate the level of eosinophils.
  4. Medications: To reduce inflammation and ease symptoms.

Key Points

Aspect Details
Eosinophils White blood cells that increase during inflammatory processes.
Eosinophilic Esophagitis (EoE) Inflammatory condition with elevated eosinophils in the esophagus.
Egg Protein A common trigger for EoE, leading to eosinophil accumulation.
Immune Response Both IgE and non-IgE mediated responses can contribute to the condition.
Diagnosis Typically involves endoscopy with biopsy and allergy testing.
Management Diet changes, medications, and monitoring by a healthcare provider.

In summary, if someone is experiencing symptoms suggestive of EoE, especially after eating eggs, it is important to seek medical advice. Egg protein is a common trigger and can cause an elevation of eosinophils in the esophagus.

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