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Do nails have DNA?

Published in Forensic Biology 2 mins read

Yes, nails contain DNA. Although nails are primarily composed of a protein called keratin, they also contain DNA from the skin cells surrounding the nail bed. This DNA can be used for various purposes, including genetic testing, paternity testing, and even forensic investigations.

Researchers have successfully extracted DNA from nail clippings, yielding an average of 544 ng of DNA per 6.3 milligrams of nail. This demonstrates the viability of using nail clippings as a source of genetic material. While extracting DNA from nails can be more challenging compared to other sources, it provides a readily available and non-invasive option for obtaining genetic information.

Here's a breakdown of how nail DNA testing works:

  • Nail Collection: Individuals are instructed to collect their nail clippings using a clean method.
  • DNA Extraction: Special procedures are used to separate and purify the DNA from the keratin and other cellular components in the nail.
  • DNA Analysis: Once extracted, the DNA can be analyzed for various purposes like:
    • Paternity Testing: Establishing biological relationships between individuals.
    • Genetic Testing: Identifying genetic markers for inherited diseases or traits.
    • Forensic Investigations: Matching DNA evidence from crime scenes with potential suspects.

The use of nail DNA is particularly beneficial in situations where traditional blood or saliva samples are not available or practical.

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