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What are the Main Causes of Colitis?

Published in Gastrointestinal Health 2 mins read

The main causes of colitis include infections, inflammatory bowel diseases, reduced blood flow to the colon, and past radiation exposure. Colitis refers to inflammation of the colon, and the underlying cause can vary widely.

Here's a breakdown of the common causes:

  • Infections:
    • Viral or Parasitic Infections: Certain viruses and parasites can infect the colon, leading to inflammation and colitis symptoms. This type of colitis is often self-limiting or resolves with appropriate treatment of the infection.
    • Bacterial Infections (Food Poisoning): Bacteria like E. coli, Salmonella, Shigella, and Campylobacter are frequently associated with food poisoning and can cause colitis.
  • Inflammatory Bowel Disease (IBD):
    • Ulcerative Colitis: This is a chronic inflammatory condition that specifically affects the colon and rectum. It causes inflammation and ulcers (sores) in the lining of the large intestine.
    • Crohn's Disease: While Crohn's disease can affect any part of the digestive tract, it commonly involves the colon. It's characterized by inflammation that can penetrate deep into the layers of the bowel tissue.
  • Ischemic Colitis:
    • Reduced Blood Flow: This condition occurs when the colon doesn't receive enough blood flow, leading to inflammation and damage. This can be caused by narrowed or blocked arteries, low blood pressure, or other vascular problems.
  • Radiation Colitis:
    • Past Radiation to the Colon: Radiation therapy targeting the abdomen or pelvis can damage the colon and cause inflammation. This can occur during or shortly after radiation treatment, or it can develop months or even years later. Radiation strictures can also form.
  • Necrotizing Enterocolitis (NEC):
    • Premature Infants: This serious condition primarily affects premature newborns and involves inflammation and damage to the intestinal lining. While it can affect the small intestine, it can also involve the colon.

In summary, colitis can result from a variety of factors, including infectious agents, inflammatory conditions, insufficient blood supply, and radiation exposure. Identifying the specific cause is crucial for effective treatment and management.

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