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What is the Cry Baby Syndrome?

Published in Genetic Disorders 2 mins read

Cry baby syndrome, more accurately known as Cri-du-chat syndrome, is a rare genetic condition. It's not a "syndrome" of being overly emotional but rather a specific chromosomal disorder.

Understanding Cri-du-chat Syndrome

Cri-du-chat syndrome, also called 5p- (5p minus) syndrome, arises when a portion of chromosome 5 is missing. This missing piece disrupts normal development, leading to several characteristic features, particularly in infancy. The most noticeable of these is a high-pitched cry that sounds remarkably like a cat's meow, hence the name "Cri-du-chat," which is French for "cry of the cat."

Key Features of Cri-du-chat Syndrome:

  • Characteristic Cry: Infants with this syndrome have a very distinctive, high-pitched cry due to problems with the larynx (voice box).
  • Facial Features: They often have small heads (microcephaly), wide-set eyes, a low-set nose, and a small jaw.
  • Developmental Delays: Cri-du-chat syndrome is usually associated with intellectual disability, delayed motor skills, and speech problems.
  • Other Health Issues: Some infants may also have heart defects, feeding difficulties, and other health issues.


Feature Description
Cry High-pitched, like a cat's meow
Chromosomal Basis Missing piece of chromosome 5
Facial Characteristics Small head, wide-set eyes, low-set nose, small jaw
Development Intellectual disability, delayed motor skills and speech
Other Issues Heart defects, feeding problems, other health complications (sometimes)


Important Note: Cri-du-chat syndrome is a genetic condition caused by a chromosomal deletion, not a psychological or behavioral issue. This means that "Cry baby syndrome" is a misnomer and should not be confused with someone who is simply expressing emotions frequently.

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