ADP illness, or ALAD Porphyria (ADP), is a very rare genetic metabolic disease. It results from a severe deficiency in the enzyme delta-aminolevulinic acid (ALA) dehydratase.
Understanding ALAD Porphyria (ADP)
ALAD Porphyria (ADP) involves a deficiency of the enzyme δ-aminolevulinic acid dehydratase, which is produced by the ALAD gene. The deficiency impacts the body's ability to produce heme, a component of hemoglobin.
Key Aspects of ADP:
- Genetic Origin: ADP stems from mutations in the ALAD gene.
- Enzyme Deficiency: Individuals with ADP have a significant lack of the ALA dehydratase enzyme.
- Metabolic Impact: The deficiency affects the heme production pathway.
- Rarity: ADP is an exceptionally rare condition.
