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What are the causes of genetic mutations?

Published in Genetic Mutations 2 mins read

Genetic mutations arise from several key sources, leading to alterations in an organism's DNA. These changes can have various consequences, depending on the type and location of the mutation.

Understanding Genetic Mutation Causes

Mutations are changes in the DNA sequence and they can be caused by:

  • Errors in DNA Replication: During cell division, DNA must be copied, and this process is prone to errors. These errors, if not corrected, can lead to new mutations. This is explained in the reference material that states "Mutations can result from errors in DNA replication during cell division".

  • Exposure to Mutagens: Mutagens are external agents that can damage DNA. This can include:

    • Chemicals: Certain chemicals found in the environment or produced by industrial processes can damage DNA, leading to mutations.
    • Radiation: Exposure to radiation like UV radiation from the sun or X-rays can cause DNA damage.
    • Viruses: Some viral infections can also lead to mutations by inserting viral DNA into the host's genome. The reference mentions that "Mutations can result from... exposure to mutagens or a viral infection."

Types of Mutations and Inheritance

Mutations can also be classified based on where they occur:

  • Germline Mutations: These mutations occur in reproductive cells (eggs and sperm) and are heritable. This means they can be passed from parents to offspring.
  • Somatic Mutations: These mutations occur in body cells (somatic cells) and are not passed on to the next generation. These can occur any time during a person's life, and can contribute to conditions such as cancer.

Summary of Causes

Cause Description
Errors in DNA replication Mistakes made when DNA is copied during cell division.
Exposure to Mutagens Damage caused by external factors like chemicals and radiation.
Viral Infections Insertion of viral DNA into the host's genome.

It is important to understand that these mutations are part of the natural biological process and are a source of genetic variation, which is essential for the evolution of life.

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