The symptoms of Xq28, particularly in males, include a range of cognitive, behavioral, physical, and immunological issues. Based on the provided reference, here's a breakdown:
Symptoms of Xq28
Xq28 is a rare, syndromic X-linked intellectual disability with the following key symptoms, especially prominent in males:
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Cognitive Impairment: This includes intellectual disability of varying degrees.
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Behavioral and Psychiatric Problems: These can manifest as a variety of issues requiring specialized care.
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Obesity: Patients may be prone to weight gain and obesity.
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Recurrent Infections: Increased susceptibility to infections.
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Atopic Diseases: Increased risk of allergic conditions such as eczema, asthma, and allergic rhinitis.
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Distinctive Facial Features: The syndrome can result in specific facial characteristics that aid in diagnosis.
