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Do you lose Y chromosomes with age?

Published in Genetics and Aging 2 mins read

Yes, males can lose Y chromosomes in some of their cells as they age.

Y Chromosome Loss in Aging Males

The loss of the Y chromosome is a phenomenon that primarily affects biological males as they get older. While most cells in males typically have one X and one Y chromosome, this can change over time.

Details About Y Chromosome Loss

  • Occurrence: Some cells in males lose their Y chromosome naturally with age.
  • Prevalence: More than half of males in their early 90s have lost the Y chromosome in some of their blood cells.
  • Why it happens: This is a natural process linked to aging, and can be thought of as genetic changes accumulating over time.

Key Facts:

Aspect Details
Typical Male Chromosomes One X and one Y chromosome
Chromosome Loss Some cells lose the Y chromosome as males age
Rate of Loss More than 50% of males in their early 90s have experienced some Y chromosome loss in their blood cells

What this means for Males

While the loss of a Y chromosome in some cells does not make a male "female", it is a notable biological change associated with aging.

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