TDF in biology refers to Testis-Determining Factor, which is actually the same as the Sex-determining region Y protein (SRY).
Understanding Testis-Determining Factor (TDF)
TDF, or Testis-Determining Factor, plays a crucial role in male sex determination in therian mammals (placental mammals and marsupials). It is encoded by the SRY gene and functions as a DNA-binding protein (also known as gene-regulatory protein/transcription factor).
Key Aspects of TDF/SRY
Here's a breakdown of important information regarding TDF/SRY:
- Function: Initiates male sex determination.
- Encoding Gene: Encoded by the SRY gene.
- Protein Type: DNA-binding protein/transcription factor.
- Species: Found in therian mammals (placental and marsupial mammals).
- Synonym: Also known as Sex-determining region Y protein (SRY).
TDF/SRY in Sex Determination
The presence or absence of a functional SRY gene, which produces TDF, determines the development of the gonads into testes or ovaries, respectively.
