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How Do I Know My Genes?

Published in Genetics & DNA 4 mins read

You can learn about your genes through genetic testing, which analyzes your DNA to identify variations and provide insights into ancestry, health risks, and traits.

Here's a breakdown of how you can access and understand your genetic information:

Types of Genetic Testing

Several types of genetic tests are available, each providing different kinds of information:

  • Ancestry Testing: These tests analyze specific DNA markers to determine your ethnic origins and connect you with living relatives. Companies like AncestryDNA and 23andMe offer this type of testing. They often involve analyzing autosomal DNA, which is inherited from both parents and provides a broad overview of your ancestry.
  • Health Risk Testing: These tests assess your predisposition to certain diseases and conditions, such as heart disease, Alzheimer's disease, and certain types of cancer. 23andMe also offers health risk testing, subject to regulatory approval. Keep in mind that these tests provide risk assessments, not diagnoses.
  • Diagnostic Testing: This type of testing confirms or rules out a specific genetic condition. It's often ordered by a doctor and performed in a clinical setting. Examples include testing for cystic fibrosis or Huntington's disease.
  • Pharmacogenomic Testing: This testing analyzes how your genes affect your response to certain medications. This information can help your doctor choose the most effective medications and dosages for you.
  • Mitochondrial DNA Testing: Identifies genetic variations in mitochondrial DNA, which is inherited from your mother and can provide information about your maternal lineage. MedlinePlus explains more about this.

How to Get Genetic Testing

  1. Direct-to-Consumer (DTC) Testing: You can purchase kits online or in stores. You typically provide a saliva sample that is mailed to the company's lab for analysis.
  2. Clinical Genetic Testing: Your doctor can order genetic testing if they suspect you have a genetic condition or want to assess your risk for certain diseases. This testing is usually more comprehensive and may involve blood samples.

Understanding Your Results

  • Ancestry Reports: These reports typically include a breakdown of your ethnic origins, often presented as percentages. They may also connect you with potential relatives in the company's database.
  • Health Risk Reports: These reports indicate your risk of developing certain diseases based on your genetic profile. It's important to remember that these are just risk assessments, and other factors like lifestyle and environment also play a role. Consult with a healthcare professional to interpret these results.
  • Genetic Counseling: Consider meeting with a genetic counselor to discuss your results and understand their implications. They can provide personalized advice and help you make informed decisions about your health.

Important Considerations

  • Accuracy: Genetic tests are generally accurate, but errors can occur. It's important to choose a reputable testing company.
  • Privacy: Be aware of the privacy policies of the testing company and how your genetic information will be used and stored.
  • Emotional Impact: Genetic testing can reveal unexpected or unsettling information about your ancestry or health risks. Be prepared for the emotional impact and seek support if needed.

By understanding the different types of genetic tests and how to interpret the results, you can gain valuable insights into your ancestry and health. Always consult with healthcare professionals to make informed decisions based on your genetic information.

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