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What does TT mean in DNA?

Published in Genetics Notation 3 mins read

The notation "TT" in the context of DNA and genetics typically signifies a homozygous dominant genotype. However, based on the provided reference which only discusses heterozygous conditions using the notation "Tt", it's important to clarify. The reference focuses on situations where an individual has two different versions (alleles) of a gene – one dominant and one recessive, as in "Tt". The reference does not discuss the situation where an individual has two identical versions (alleles) of a gene, which is where the notation "TT" would be relevant.

Understanding Genetic Notation

In genetics, we use letters to represent different versions of a gene, known as alleles. Capital letters usually represent dominant alleles and lowercase letters represent recessive alleles. Here's a breakdown:

Homozygous vs. Heterozygous

  • Homozygous: Means an individual has two identical alleles for a particular gene. This can be either homozygous dominant (e.g., TT) or homozygous recessive (e.g., tt).

    • Homozygous Dominant (TT): An individual possesses two dominant alleles for a particular gene. The dominant trait will be expressed.
    • Homozygous Recessive (tt): An individual possesses two recessive alleles for a particular gene. The recessive trait will be expressed only in the homozygous recessive state.
  • Heterozygous: As mentioned in the reference, this means an individual has two different alleles for a particular gene (e.g., Tt). In this case, the dominant allele's trait will typically be expressed.

The Reference Context

The provided reference states:

The notation Tt means the heterozygous condition in genetics. In this condition a homologous pair contains different alleles of a gene. One homologous chromosome possesses the recessive allele and the other chromosome possesses the dominant allele present for a gene.

This context implies that if "T" represents a dominant allele and "t" represents a recessive allele, the combination "Tt" will result in the expression of the dominant trait. It directly clarifies the heterozygous condition. However, it does not directly describe "TT".

Clarifying "TT"

To be clear:

  • The combination TT would mean an individual is homozygous dominant for that particular gene. This means that they carry two copies of the dominant allele. Consequently, the dominant trait would be expressed.

Example

Let's take an example: if 'T' represents the allele for tallness in a plant and 't' represents the allele for shortness, then:

  • TT would be a tall plant (homozygous dominant).
  • Tt would also be a tall plant (heterozygous), as stated in the reference.
  • tt would be a short plant (homozygous recessive).

Summary Table

Genotype Description Trait Expression
TT Homozygous dominant Dominant trait
Tt Heterozygous Dominant trait
tt Homozygous recessive Recessive trait

In conclusion, the combination TT represents the homozygous dominant condition where two dominant alleles are present at a specific gene locus and the dominant trait is expressed. The provided reference only explicitly explained the heterozygous condition using the "Tt" notation.

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