Can XYY Get Pregnant?
No, individuals with XYY syndrome cannot get pregnant.
XYY syndrome is a genetic condition affecting only males. It's characterized by the presence of an extra Y chromosome, resulting in a 47,XYY karyotype instead of the typical 46,XY. While many individuals with XYY syndrome have normal sexual development and fertility (as stated in the provided text: "Most boys with XYY syndrome can grow up healthy, have normal sexual development and fertility, and lead productive lives." ), they are still biologically male and lack the necessary reproductive organs to carry and deliver a pregnancy.
While some males with XYY syndrome may experience fertility issues such as decreased sperm count (https://www.healthline.com/health/xyy-syndrome), this does not change the fundamental biological impossibility of pregnancy. In fact, assisted reproductive technologies like IVF or ICSI might be necessary for some individuals with XYY syndrome to father children (https://journals.lww.com/md-journal/fulltext/2020/02280/reproductive_outcomes_of_3_infertile_males_with.82.aspx). This highlights that they are capable of contributing genetically to offspring but cannot carry a pregnancy themselves.
Prenatal screening methods, such as chorionic villus sampling (CVS), can detect XYY syndrome during pregnancy (https://www.cdph.ca.gov/Programs/CFH/DGDS/CDPH%20Document%20Library/PNS%20Documents/XYY_Screen_Positive_Booklet_English.pdf). This screening, however, is performed to check the fetus, not the pregnant individual who is necessarily a female with XX chromosomes.
