The DCC gene provides instructions for making a protein, the netrin-1 receptor, that plays a crucial role in the development of the nervous system.
Function of the DCC Gene and Netrin-1 Receptor
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Nervous System Development: The DCC (Deleted in Colorectal Carcinoma) gene is vital for guiding nerve cells (neurons) to their correct locations during the formation of the nervous system. This process relies on the netrin-1 receptor protein produced by the DCC gene.
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Netrin-1 Interaction: The netrin-1 receptor interacts with a signaling molecule called netrin-1. This interaction acts like a directional cue, attracting growing nerve cells towards their intended destinations.
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Cell Communication: The DCC gene helps cells communicate with each other during development.
Implications of DCC Gene Mutations
Mutations in the DCC gene can disrupt the normal development of the nervous system. This can lead to a variety of health problems.
In Summary
The DCC gene is essential for proper nervous system development, acting through the netrin-1 receptor to guide nerve cells to their correct locations.
