Gluconeogenesis, the process of creating glucose from non-carbohydrate sources, is stimulated by diabetogenic hormones according to provided reference.
Factors Stimulating Gluconeogenesis
Several factors can stimulate gluconeogenesis. The most prominent ones are:
- Hormones: These include the "diabetogenic hormones":
- Glucagon: Signals low blood glucose levels.
- Growth Hormone: Influences glucose metabolism.
- Epinephrine (Adrenaline): Released during stress or exercise.
- Cortisol: A stress hormone that increases glucose availability.
- Substrates: The availability of gluconeogenic substrates also plays a key role. These substrates include:
- Glycerol
- Lactate
- Propionate
- Certain Amino Acids
Role of Gluconeogenesis
Gluconeogenesis is essential for maintaining plasma glucose levels, especially between meals when glucose from food is not readily available. It ensures a continuous supply of glucose to the brain and other tissues that rely heavily on it for energy.
