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How is glucose broken down?

Published in Glucose Metabolism 2 mins read

Glucose is primarily broken down through a process called glycolysis.

Here's a breakdown of how it happens, based on the provided reference:

Glycolysis is the initial stage of glucose breakdown and it occurs in the cytoplasm of the cell. Here's how it works:

  • Initial Investment: The process starts with a glucose molecule (containing six carbon atoms). To kickstart the process, two molecules of ATP are used (hydrolyzed) to provide the necessary energy.

  • Splitting the Sugar: The glucose molecule is then broken down into two molecules of pyruvate. Each pyruvate molecule contains three carbon atoms. So the six-carbon glucose molecule is split into two three-carbon pyruvate molecules.

  • Energy Production: While the early steps require an investment of ATP, later steps generate ATP. In fact, four molecules of ATP are produced for each molecule of glucose that undergoes glycolysis.

  • Net Gain: Because two ATP molecules were initially used and four are produced, there is a net gain of two ATP molecules per glucose molecule during glycolysis.

In summary, glycolysis converts one glucose molecule into two pyruvate molecules, resulting in a net gain of two ATP molecules.

Step Description ATP Consumed ATP Produced
Initial Investment 2 ATP molecules are hydrolyzed to provide energy. 2 0
Glucose to 2 Pyruvate Glucose molecule is broken down into two pyruvate molecules. 0 4
Net Result Conversion of glucose to pyruvate with a net production of ATP molecules. 2 4

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